The Synthesis of hydroxyapatite from Red Snapper (Lutjanus campechanus) fish bone carried out. Hydroxyapatite is utilized for Cd(II) sorption from solution using a fixed-bed column. Hydroxyapatite was characterized using X-ray Diffraction, Fourier Transform Infra-Red, Scanning Electron Microscope-Electron Dispersive, and Thermogravimetric. In fixed-bed column, the influence of bed height (5, 10, 15 cm) and flow rate (6, 8 and 10 mL/min) were studied. The highest adsorption capacity is obtained at a bed height of 15 cm, and a flow rate of 6 mL/min with adsorption capacity is 47.027 mg/g. The predicted by Bed Depth Service Time (BDST) model obtained that value of R2 in the range 0.9964-0.9997. The adsorption capacity per unit volume ( is in the range 141.12-222.89 mg/L while  is in the range 0.0136-0.022 L/mg h. This indicates that BDST can be used to explain the performance of Cd(II) sorption onto hydroxyapatite by fix-bed column.
                        
                        
                        
                        
                            
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