Journal SAGO Gizi dan Kesehatan
Vol 2, No 1 (2020): Juli - Desember

Pengaruh pemberian obat anti tuberkulosis dengan vitamin D terhadap perubahan BTA pada penderita tuberkulosis paru di Kabupaten Pidie

Rina Maulidar (Program Studi Magister Kesehatan Masyarakat, Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah, Aceh)
Nurjannah Nurjannah (Fakultas Kedokteran, Universitas Syiah Kuala, Aceh)
Aulina Adamy (Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah, Aceh)
Iskandar Iskandar (Jurusan Gizi, Polteknik Kesehatan Kemenkes Aceh, Aceh)



Article Info

Publish Date
23 Dec 2020

Abstract

Background: Tuberculosis (TB) is a global health problem, Indonesia had the second rank of the case in the world after India which is the fourth cause of death. Giving vitamin D together with anti-tuberculosis drugs can increase healing proses because vitamin D (anti-microbial immunomodulators) kills Mycobacterium tuberculosis.Objectives: This study aims to measure the effect of giving anti-tuberculosis drugs with vitamin D on changes in AFB in patients with pulmonary tuberculosis.Methods: This study was used a quasi-experiment design, pre-test and post-test control group was doing at 25th March – 25th July 2019. This research has been conducted in Pidie Regency. The intervention group (17 samples with tuberculosis drugs) was given Softgels vitamin D 5000 IU for 4 months, while the control group was only anti-tuberculosis drug therapy. The data were analyzed statistically using the Wilcoxon and Mann Whitney tests at a significance level of 95%.Results: Before the intervention, the BTA status of both the intervention and control group was similar (p= 0.061). After the intervention, there was a decrease in AFB interactions (p= 0.000). There was a decrease in the contribution of AFB in the control group before with after intervention (p= 0.000). There are those who support (p= 0.033) giving vitamin D the acceleration of pulmonary tuberculosis treatment. Conclusion: It is better to administer vitamin D to the successful treatment of pulmonary TB in patients undergoing anti-tuberculosis drug therapy.

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Journal Info

Abbrev

gikes

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

Journal of SAGO Gizi dan Kesehatan (Nutrition and Health) is a peer-reviewed journal of a scientific nature contained in the Polytechnic of Health Ministry of Health of Aceh, who publish high quality of nutrition and health-related individuals, populations, groups and communities who are vulnerable ...