This paper offers several insights regarding the principles of qualitative research method, defining how itshape the empirical process as well as knowledge acquisition in biology and science research. The first partof the paper will briefly compare the assumptions, techniques, strengths and weaknesses of the quantitativeand qualitative research paradigms.These paradigms are examined in terms of past trends in biology andscience education research indicating a shift in approach from quantitative to qualitative over the last severaldecades. The core thesis of the paper contends the emerging trends of qualitative research to advance ourunderstanding of what it takes to more systemically and effectively improve programs, curriculum, tosynthesize new directions for research and to communicate a straightforward and unified message about theimpact and success in Biology and Science education. To conclude, issues on the horizon that represent newchallenges, opportunities, strategies, and technologies in qualitative research will be addressed anddeliberated.
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