The Effectiveness of Curcuma zedoaria Extract in Enhancing Non Spesific Immune Responses of Tiger Grouper (Epinephelus fuscoguttatus)

Agus Putra A. Samad (Department of Aquaculture Faculty of Agriculture, Universitas Samudra, Jl. Prof. Dr. Syarief Thayeb, Meurandeh, Langsa Lama, Langsa City, Aceh)
Eva Ayuzar (Department of Aquaculture Faculty of Agriculture Universitas Malikussaleh, Jl. Cot Tengku Nie, Reuleut, Muara Batu, Aceh Utara, Aceh 24355, Indonesia)
Ilhamdi Ilhamdi (Politeknik Kelautan dan Perikanan Pariaman, Jl. Simpang Toboh V Koto, Kampung Dalam, Pasir, Pariaman Tengah, Kota Pariaman, Sumatera Barat 25501, Indonesia)
Muhammad Hatta (Department of Aquaculture Faculty of Agriculture Universitas Malikussaleh, Jl. Cot Tengku Nie, Reuleut, Muara Batu, Aceh Utara, Aceh 24355, Indonesia)

Journal of Aquaculture and Fish Health
Vol. 11 No. 1 (2022): JAFH Vol. 11 No. 1 February 2022

The present study was conducted to determine the effect of using turmeric extract (Curcuma zedoaria) on non specific immune of grouper (Epinephelus fuscoguttatus). During the study, fish were fed a diet containing 0, 0.5, 1.0, 2.5 g extract/kg feed twice a day for 14 days. Observations of non-specific immune parameters such as respiratory burst activity, chemiluminescent response, phagocytic activity, superoxidase dismutase (SOD) and lysozyme activity were sampled at 0, 1, 2, 4, 7 and 14 days. The results showed that fish fed C. zedoaria with 0.5 g/kg feed affected non-specific immune responses, and showed significant effect in the short term. On contrary, for long-term administration causes a decrease and inhibition of non-specific cellular defense activity. Thus, this study concluded that the administration of turmeric extract added to the feed can act as an immunostimulant and increase the non-specific immune response in grouper (E. fuscoguttatus).