This study aims to find out what problems affect the anxiety of health workers in handling COVID-19. This research design uses a quantitative research design with a cross-sectional approach. The results of the study found that several factors that were suspected of having anxiety problems in handling COVID-19 that had a relationship were age (0.044), family status (0.037), and knowledge of health workers (0.000). At the same time, the variables of gender, education, years of service, advice, and infrastructure have no relationship with the anxiety problems of health workers in handling COVID-19. In conclusion, there is a relationship between age, family status, and knowledge of anxiety handling COVID-19. Keywords: COVID-19, Anxiety, Health Workers
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