ad-Dawaa : Journal of Pharmaceutical Sciences
Vol 4 No 2 (2021)

Potential of Modified Cassava Starch as a Tablet Binder in Direct Compression Method

Wira Noviana Suhery (Sekolah Tinggi Ilmu Farmasi Riau)
Anita Lukman (Unknown)
Afriyanti Afriyanti (Unknown)



Article Info

Publish Date
30 Dec 2021

Abstract

Research on the potential of modified cassava starch as a binder for the direct compression method has been carried out. The use of modified cassava starch as a binder using six formulas with the drug model ibuprofen. Variations in the concentration of modified cassava starch were modified cassava starch 48 and modified cassava starch 72 were 15%, 17.5%, and 20%, respectively. The formula with a modified starch 72 concentration (15%) is the best formula that produced optimal tablets. The value of hardness was 5.3 kg/cm2, friability of 0.90%, and disintegration time of 2.06 minutes which are the main parameters of the binder

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Journal Info

Abbrev

addawaa

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

ad-Dawaa Journal of Pharmaceutical Sciences (DJPS) merupakan jurnal yang terbit dua kali dalam setahun, yaitu setiap Juni dan Desember. Jurnal ini fokus pada seluruh bidang terkait ilmu farmasi, termasuk biologi farmasi, farmakokimia, farmakologi, farmasi klinik dan teknologi farmasi. Jurnal ini ...