<![CDATA[Enterokolitis nekrotikans (EKN) ialah peradangan berat saluran pencernaan yang terjadi pada 5-7% neonatus prematur. EKN merupakan penyebab utama morbiditas dan mortalitas di NICU. Patofisiologi multifaktorial dan belum sepenuhnya diketahui. Deteksi dini sulit karena manifestasi klinis sulit dibedakan dan masih tergantung pada radiologi abdomen yang kurang sensitif. Patofisiologi dan pendekatan diagnosis menjadi topik penelitian prioritas di bidang neonatologi saat ini. Strategi pencegahan dan tatalaksana komprehensif diharapkan dapat ditemukan agar memperbaiki luaran penyakit.Necrotizing enterocolitis (NEC) is a serious inflammatory disease of intestine which affects 5-7% preterm neonates. NEC is the leading cause of morbidity and mortality in NICU despite rapid advance in preterm neonatal care. Pathophysiology of NEC is multifactorial and not fully understood. Early detection is challenging because of indistinguishable clinical manifestation and still relies on less sensitive abdominal radiography. Nowadays, pathophysiology and diagnostic approach are priority topics for research in neonatology. Comprehensive prevention and treatment strategies expectedly can improve outcome of disease.]]>
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