Effect of Virgin Coconut Oil from Green Coconut on High-Density Lipoprotein (HDL) Levels in Blood Serum of White Mice

Iswendi Iswendi (Department of Chemistry, Faculty of Mathematics and Natural Science (FMIPA), Universitas Negeri Padang, Padang, Indonesia)
Iryani Iryani (Department of Chemistry, Faculty of Mathematics and Natural Science (FMIPA), Universitas Negeri Padang, Padang, Indonesia)
Regi Fadila Putra (Graduate School of Science and Engineering, Kansai University, Osaka, Japan.)

EKSAKTA: Journal of Sciences and Data Analysis
VOLUME 2, ISSUE 2, August 2021

This study aims to determine the effect of High-Density Lipoprotein (VCO) dose on mice's blood serum High-Density Lipoprotein (HDL) levels. This study is an experimental study using 24 mice divided into four groups. Control (-), Control (+) were fed egg yolks 0.025 mL/g body weight, Dose 0.02 and Dose 0.025 were experimental groups, given egg yolks 0.025 mL/g mice body weight and VCO at a dose of 0.020 mL, and 0.025 mL/g body weight of mice. HDL levels were determined on days 7, 14, and 21 by enzymatic method using 20 D* spectrophotometry. The statistical test found that the length of time giving VCO significantly affected blood serum HDL levels in mice with Fcount > Ftable (Fcount = 7.128 and Ftable = 5.14). In contrast, variations in VCO dose did not significantly affect blood serum HDL levels. mice with Fcount < Ftable (Fcount = 3.33 and Ftable = 4.76). The highest HDL level was at a dose of 0.020 mL/g body weight of mice with a treatment period of 14 days, namely 164,033 mg/dL of blood.