Anticancer Evaluation of Plants from Indonesian Tropical Rain Forests

Abbas, Jamilah ( Research Centre for Chemistry, Indonesian Institute of Sciences PUSPIPTEK. Serpong. 15314. Indonesia)

Indonesian Journal of Cancer Chemoprevention
Vol 2, No 3 (2011)

The  anticancer  activities  of  medicinal  plants  from Indonesia’s tropical rainforests were investigated  against  Hela  cell  line.  Maytenfoliol  from  leaves  of  Calophyllumtetrapterum  3-epibetulinic  acid  from  stem  bark  of    C.  tomentosum Wight  and  D.A-friedo-oleanan-3-on  from stem bark of C. moonii showed anticancer activity. The compound 3-epibetulinic acid showed the more potent anticancer activity than maytenfoliol  and D.A-friedo-oleanan-3- with thean IC50  value were 3.17 μg/mL, 4.89 μg/mL and 5.63 μg/mL, respectively.Keywords: Anticancer  evaluation,  Hela  cell  line, Calophyllumtetrapterum.  C.  tomentosum Wight and  C. moonii