2’,4’-Dihidroksi-3’,5’,6’-Trimetoksi Calkon suatu Senyawa Antitumor dari Kulit Batang Tumbuhan Cryptocarya costata (Lauraceae)

Hanapi Usman ( Departemen Kimia Universitas Hasanuddin Makassar)
Euis Holisotan Hakim ( Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, FMIPA ITB)
Sjamsul Arifin Achmad ( Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, FMIPA ITB)
Tjodi Harlim ( Departemen Kimia Universitas Hasanuddin Makassar)
Muhammad N. Jalaluddin ( Departemen Kimia Universitas Hasanuddin Makassar)
Yana Maolana Syah ( Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, FMIPA ITB)
Lia Dewi Juliawati ( Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, FMIPA ITB)
Lukman Makmur ( Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, FMIPA ITB)
Mariko Katajima ( Center for Medicinal Resources, Faculty of Pharmaeutical,Chiba University)

Jurnal Matematika & Sains
Vol 10, No 3 (2005)

Sifat Listrik Film Tipis SrTiO3 untuk Kapasitor MOS An anti-tumor calcon has been isolated from Criptocarya costata stem bark. The compound was obtained from chloroform fraction fractioned by chromatography technique and recrystalized in n-hexane and ethyl acetate. The compound structure elucidated based on physical and spectroscopic data was 2,4-dihydroxy-3,5,6-trimethoxy calcon. Cytotoxic assay using murine leukemia cell P388 showed positive activity with IC50 value of 3.65 µg/mL.