Jurnal RSMH Palembang
Vol. 1 No. 2 (2020): Jurnal RSMH Palembang

Insulinoma

Ria Yuniarti (Unknown)
Suly Auline (Departemen Patologi Anatomi, Fakultas Kedokteran Universitas Sriwijaya, Palembang, Indonesia)



Article Info

Publish Date
15 Dec 2020

Abstract

A B S T R A C TInsulinoma is a functional neuroendocrine neoplasm consisting of insulin-producingcells, which produce insulin uncontrollably, causing a hypoglycemic syndrome. TheHypoglycemic syndrome is a result of hyperinsulinemia which causes adrenergicsymptoms and neuroglycopenia. The clinical diagnosis is based on the Whipple triad,insulin, and C peptide levels in a 72-hour fasting state. Generally, insulinoma is abenign neoplasm with a proliferation index of Ki-67 <2%. On histological features, thegrowth pattern of the insulinoma is usually trabecular or solid. Some insulinomas showa tubuloacinar growth pattern with psammoma bodies. We reported one case ofinsulinoma in a 65-year-old woman, who had experienced fainting, cold sweats for 3years, especially when the patient ate late or at midnight while sleeping. A CT scanshowed a tumor mass in the pancreas possibly an insulinoma and a pancreatectomywas performed. The results of the histopathological examination are bu following peerunder Insulinoma.

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Journal Info

Abbrev

JRP

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

JRP covers the major topics like Internal Medicine, Obstetric and Gynecology, Pediatric, Surgery, Ear Nose Throat, Neurology, Ophthalmology, Dermatovenerology, Anesthesia and Reanimation, Radiology, Pathology Anatomy, Clinical Pathology, Community Enpowerment, Manajemen of Hospital, Community ...