Jurnal Buana Farma
Vol. 2 No. 1 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi

SKRINING FITOKIMIA DAN UJI ANTIBAKTERI Streptococcus mutans DARI EKSTRAK DAUN KANGKUNG PAGAR (Ipomoea carnea Jacq)

Alifah Rahmania Fadhilah (Fakultas Farmasi Universitas Buana Perjuangan Karawang)
Dedeh Komalasari (Fakultas Farmasi Universitas Buana Perjuangan Karawang)
Ermi Abriyani (Fakultas Farmasi Universitas Buana Perjuangan Karawang)
Iin Lidia Putama Mursal (Fakultas Farmasi Universitas Buana Perjuangan Karawang)



Article Info

Publish Date
14 Apr 2022

Abstract

Dental caries is one of the most common dental health problems and is the main problem of dental and oral disease. the most common cause of dental caries is Streptococcus mutans bacteria. To treat dental caries, one of the plants that can be used is the leaf of kale fence (Ipomoea carnea Jacq, which has antibacterial properties. This study aims to determine the compound content of n-hexane, methanol, ethyl acetate and the antibacterial activity of Streptococcus mutans. This research used well diffusion method and tested against Streptococcus mutans bacteria. Thus, it was found that the compound content of the thick extract of kale leaves contains compounds of steroidal n-hexane, methanol flavonoids, saponins, tannins, triterpenoids, and ethyl acetate alkaloids, flavonoids, steroids, tannins and simplicia dried kale leaves contain alkaloids, flavonoids. , steroids, tannins. The results of the activity test of the leaf extract of kale (Ipomoea carnea Jacq) inhibited the growth of Streptococcus mutans bacteria with a concentration of 100% n-hexane inhibition zone 5.2 mm in the weak category, methanol 16.4 mm in the very strong category and ethyl acetate 10.4 mm in the strong category. . Based on the results, it was shown that the leaf of kale (Ipomoea carnea Jacq) had antibacterial activity from Streptococcus mutans bacteria.

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Journal Info

Abbrev

buanafarma

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical ...