<![CDATA[During pandemic, learning process changed into online method which often cause musculoskeletal complaint. This research aimed to discover the effect of isometric and isotonic exercises to nonspecific muscle pain on college students who went through online learning process. This study used qualitative quasi experiment to observe changes after exercise. The subjects were 40 college students aged 20-22 years old. Visual Analog Scale was used to measure paim grade before and after exercise. Exercise contained of isometric and isotonic exercises on neck, shoulder and back muscles. This exercise conducted 3 times a week, within 4 weeks and the duration of exercise was 20 minutes each. After 4 weeks of exercise muscle pain changed from average scale of 4 to 1 (p=0,001) with CI 95%. Conclusion of this study is isometric and isotonic exercises has effect on nonspecific muscle pain. Keywords: isometric. Isotonic; Non Specific Muscle PainAbstrakPada masa pandemi proses pembelajaran dilakukan secara daring, sehingga menyebabkan keluhan muskuloskeletal. Penelitian ini dilakukan untuk mengetahui pengaruh latihan isometrik dan isotonik terhadap nyeri otot non spesifik pada mahasiswa yang menjalani kuliah daring. Metode yang digunakan adalah quasi eksperimen kuantitatif yaitu memberi perlakuan dan mengukur akibat perlakuan. Subyek penelitian terdiri dari 39 mahasiswa berusia 20-22 tahun. Digunakan visual analog scale (VAS) sebelum dan sesudah latihan untuk mengukur derajat nyeri subyek. Latihan terdiri dari latihan isometrik dan isotonik otot leher, bahu dan punggung sebanyak 3 kali seminggu selama 4 minggu dengan durasi 20 menit per latihan. Setelah latihan 4 minggu terdapat perubahan derajat nyeri dari rata-rata VAS 4 menjadi rata-rata 1 (nilai p=0,001) dengan CI 95%. Disimpulkan latihan isometrik dan isotonik mempunyai efek terhadap nyeri otot non spesifik. ]]>
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