Gambaran Darah pada Babi yang Diinfeksi Streptococcus suis Secara Intranasal dan Intravena

Putri Wiliantari (Dokter Hewan Praktisi di Kota Denpasar, Bali)
I Nengah Kerta Besung (Laboratorium Bakteri dan Mikologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jln. PB. Sudirman, Denpasar, Bali)
Gusti Ngurah Kade Mahardika (Laboratorium Biomedik dan Biomolekuler, Fakultas Kedokteran Hewan Universitas Udayana)

Buletin Veteriner Udayana
Vol. 14 No. 3 June 2022

Research has been carried out to elucidate clinical, as well as differences in blood profiles in pigs infected with Streptococcus suis isolated from Bali by intravenous and intranasal infection routes. S.suis isolate of PPB5 were inoculated intranasally and intravenously to three pigs respectively. The pigs used in this study were 8 weeks old. In intranasal infection before inoculation, 1% acetic acid was first applied to the nasal cavity, then S. suis inoculum was sprayed (2 x 106). In intravenous infection, inoculum fluid is injected into the auricular vein. Clinical changes in pigs were observed until day 15. Blood samples were taken before being inoculated with bacteria, 3rd day after inoculation, and before being euthanized. On the 3rd day after inoculation, the number of eosinophils was significantly different in the two treatments, while the other blood profiles were not significantly different. All blood indicators in the two treatments were not significantly different before the animals were euthanized on day 15. The increase number of erythrocytes and monocytosis was found in intranasal infections at that day. Hypohaemoglobinemia and decreased PCV are seen in both intranasal and intravenous infections. Further research is needed with a greater number of replications. The S. suis vaccine needs to be developed immediately to reduce the threat to public health and economic losses for farmers.