Indonesian Journal of Cardiology
Vol. 33, No. 3 Juli - September 2012

Kajian Kemampuan Rosela (Hisbiscus Sabdariffa) Dalam Menghambat Peningkatan Tekanan Darah Melalui Respon Vasodilator Nitrit Oksida pada Wanita Lanjut Usia penderita Hipertensi

I Yusni (Bagian Fisiologi Fakultas Ke-dokteran Universitas Syiah Kuala, Banda Aceh)
M Syahrul (Bagian Neurologi Fakultas Ke-dokteran Universitas Syiah Kuala, Banda Aceh)



Article Info

Publish Date
04 Jun 2013

Abstract

Background. Herbal medication for hypertension is common in population. This study aims to seek the role of nitric oxide (NO) in the mechanism of blood pressure reduction after  administration of rosella tea (hisbiscus sabdariffa). Methods. A pre-post study was conducted in elderly hypertensive women at UPTD Rumoh Sejahtera Banda Aceh. Subjects were given 2 grams rosella tea after meal twice a day for 3 weeks.  Sistolic and diastolic blood pressure, and NO concentration were compare pre and post rosella administration between control and experiment groups.Results. Rosela group has lower systolic and diastolic pressure as compare to control group (140,00 ± 10,00 vs 142,85 ± 4.87 mmHg; 84,28 ± 5,34 vs 89,28 ± 4,87mmHg, p < 0.05  respectively). Systolic pressure reduction by rosella was 14,77% with average pressure reduction of 24,28 mmHg. Diastolic pressure reduction was 9,22% with averagepressure reduction of 8,57 mmHg. No significant difference of nitric oxide concentration between groups (4,85 ± 2,16 vs 4,55 ± 3,11 µM, p>0.05). Conclusion. Rosella reduce systolic and diastolic blood pressure of elderly hypertensive women with mechanism out of nitric oxide level.

Copyrights © 2012






Journal Info

Abbrev

ijc

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other ...