Indonesian Journal of Cardiology
Vol. 33, No. 1 Januari - Maret 2012

Gambaran Klinis, Tampilan Ekokardiografi, dan Prediktor dari Kejadian Emboli pada Endokarditis Infektif

Muhammad Barri Fahmi (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Teuku Istia Muda Perdan (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Pranomo Sigit (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Danayu Sanni Darmawan (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Harmani Kalim (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Eka Harmeiwaty (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Amiliana Mardiyani (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Ario Soeryo (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Siska Suridanda (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)
Ganesja M Harimurti (Department of Cardiology and Vascular Medicine, Faculty of Medi-cine, University of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta)



Article Info

Publish Date
12 Jun 2013

Abstract

Background. There are many risk factors that are associated with embolic events in patients with Infective Endocarditis (IE) ranging from infecting organism, valve location, vegetation morphology, to age. Nevertheless, echocardiography role in predicting embolic events in patients with Infective Endocarditis remains controversial. Some studies reported an increased risk of embolism in patients with large and mobile vegetations, whereas other studies failed to demonstrate such a relationship.Objectives. The aim of this study is to assess the risk factors that are associated with embolic events and to evaluate the role of transthoracic echocardiography (TTE) in predicting embolic events (EEs) in a small group of patients with definite endocarditis according to the Duke criteria.Methods. Subjects more than 17 years of age, who were enrolled in National Cardiac Center Harapan Kita Infective Endocarditis Registry and who had complete TTE recording were selected for this study. Fourteenpatients with definite Infective Endocarditis according to the Duke Criteria who were hospitalised within 2010 – 2011 were examined with M-mode and  two-dimension echocardiogram. The incidence of embolism was compared with the clinical and echocardiographic characteristics (localization and mobility) of the vegetations.Results. Among 14 patients, 5 (35,7%) had one or more EEs. There were no difference between patients with and without embolism in terms of infecting organism, gender and vegetation mobility. Five out of 9 patients (55%) with mitral valve involvement vegetation had EE. No patients with only aortic and tricuspid valve vegetations had EEs. And all of the patents with EE had mitral valve involvement. Thus, there was a significant higher incidence of embolism was present in patients with mitral valve involvement of vegetation (100%, p = 0,038). Conclusion. Our study shows that the involvement of mitral valve on TTE is predictive of embolism.

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Journal Info

Abbrev

ijc

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other ...