Hiperviskositas Pada Penyakit Jantung Bawaan (PJB) Sianotik

Febtusia Puspitasari (Departement of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia National Cardiovascular Center “Harapan Kita”, Jakarta, Indonesia)
Ganesja M Harimurti (Departement of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia National Cardiovascular Center “Harapan Kita”, Jakarta, Indonesia)

Indonesian Journal of Cardiology
Vol. 31, No. 1 Januari - April 2010

Increased whole blood viscosity in adults with cyanotic congenital heart disease (CCHD) is an unavoidable result of secondary erythropoiesis and it showed a significant bleeding tendency. The most frequently disturbance of hemostasis are thrombocytopenia and defective platelet aggregation. Acute phlebotomy without volume replacement in patients with hypoxic polycythemia may result in vascular collapse, cyanotic spells, cerebral vascular accidents (CVA), or seizures and repeated phlebotomies may also increase the risk of a CVA by causing chronic iron deficiency.