Indonesian Journal of Cardiology
Vol. 33, No. 3 Juli - September 2012

Implikasi Klinis Repolarisasi Dini

Reza Octavianus (Departement of Cardiology and Vascular Medicine, Faculty of Medicine Univesity of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta.)
Yoga Yuniadi (Departement of Cardiology and Vascular Medicine, Faculty of Medicine Univesity of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta.)
Budhi Setianto (Departement of Cardiology and Vascular Medicine, Faculty of Medicine Univesity of Indonesia, and National Cardiovascular Center Harapan Kita, Jakarta.)



Article Info

Publish Date
17 Nov 2013

Abstract

Early repolarization described as J-point elevation with concaved ST segment, notch or slurred at terminal QRS complex on surface electrokardiography. This electrokardiography pattern that usually exists in young male population, for about 60 years has been concluded as benign normal variant electrokardiography. Klatsky in 2002, has strengthed this issues with his study with 1000 elecrokardiographies with early repolarization which were followed for 12 years. There was no significant case for hospitality or malignant ventricular arrhythmias among population with early repolarization comparared with normal elektrokardiography without early repolarization.But, recent studies with larger samples, show different thing, which is there was a correlation between early repolarization and malignat ventricular arrhythmias. So the issue is, whether we can still consider this early repolarization as a normal variant or not. And how about the management of asymptomatic population with early repolarization such as syncope or evidence of malignant ventricular arrhythmias.T-wave Alternans is a difference at amplitude or morphology of ST segment and T wave in every other heart beat. T-wave Alternans measurement is a non-invasive method to value cardiac cells hererogeneity. This examination has been proven to be useful as a risk stratification for malignant ventricular arrhythmias events in large studies. Higher T-wave Alternans value accompanied with higher risk for developing these arrythymias. T-wave Alternans measurement has been approved in the guideline for management of wide QRS complex tachyarrythmias for detection ventricular arrhythmias with I and IIa class of recommedantion. The more practical Modified Moving Average technicque which can be performed in healthy subjects with early repolarization is useful for risk stratification. Large studies have approved the use of Modified Moving Average for measure T-wave Alternans in these arrhythmias risk stratification.

Copyrights © 2012






Journal Info

Abbrev

ijc

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other ...