<![CDATA[The average students` score of Growth and Development in living organisms concepts was lower compared to score of the average school. This study aimed to determine the effect of Think Pair Share (TPS) cooperative learning models to increase the mastery of the students learning activities and concept mastery of Growth and Development in living organisms. This study used pretest-postest not equivalent designed applied on sample which was selected using cluster random sampling technique. The data of this study was obtained from the test (pretest and posttest) and the observation sheet (students learning activities). Data was analyzed using t-test through SPSS17 program.Based on the data analyzed, the of N-gain score of experimental class on student`s concept mastery was higher than the control class. Students learning activities used TPS model tend to increase from the first lesson to the third lesson with the average of 17.34 %.The study showed that the application of cooperative learning model type TPS affecting student`s concept mastery and learning activities on the concept of Growth and Development in living organisms. Keywords: TPS model learning, concept mastery , students` learning activities]]>
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