Acta Pharmaciae Indonesia : Acta Pharm Indo
Vol 10 No 2 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo (in progress)

Emulgel formulation of wild cherry leaves (Antidesma bunius L. Spreng) extract and its antioxidant activity

Windah Anugrah Subaidah (Department of Pharmacy, Faculty of Medicine, Mataram University, Indonesia)
Yayuk Andayani (Department of Pharmacy, Faculty of Medicine, Mataram University, Indonesia)
Dewa Ayu Puspaning Kumaradewi (Universitas Mataram)



Article Info

Publish Date
01 Aug 2022

Abstract

Background: The ethanol extract of wild cherry leaves (Antidesma bunius L. Spreng) has been studied as a free anti-radical in an emulgel formulation. The purpose of this study is to determine the physical properties of an emulgel made from an ethanol extract of wild cherry leaves, as well as its anti-radical activity. Methods: The maceration method was used to extract wild cherry leaves in 96% ethanol, which were then evaporated with a rotary evaporator. An emulgel was prepared to contain a 3.56% thick extract. The physical properties of the emulgel were evaluated consisting of the organoleptic test, pH test, homogeneity test, spreadability test, and adhesion test. The DPPH was used to test free anti-radical activity. Results: The emulgel of the ethanol extract of wild cherry leaves had a yellowish-green, thick texture, a distinct aroma of the extract, was homogeneous, pH 6, spreadability ranged from 4.4-6.2 cm, and adhesion of 5.467 0.83 cm. Emulgel had a very weak antioxidant activity with an IC50 of 6238.41 ppm. Conclusion:

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Journal Info

Abbrev

api

Publisher

Subject

Medicine & Pharmacology

Description

Journal of Acta Pharmaciae Indonesia is a journal published twice a year by Pharmacy Department, Jenderal Soedirman University, Purwokerto with the Number of ISSN 2337-8433 and E-ISSN 2621-4520. Our journal discusses various pharmaceutical fields in terms of Pharmaceutics & Pharmaceutical ...