Indonesian Journal of Cancer
Vol 14, No 2 (2020): June

The Proportion of Radiation Pneumonitis among Lung Cancer Patients in Persahabatan Hospital

Dini Rizkie Wijayanti (Department of Pulmonology and Respiratory Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta)
Jamal Zaini (Department of Pulmonology and Respiratory Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta)
Achmad Hudoyo (Department of Pulmonology and Respiratory Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta)
Aziza Ghanie (Department of Radiology Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta)
Westi ATW (Department of Radiotherapy, Persahabatan Hospital, Jakarta)



Article Info

Publish Date
01 Jul 2020

Abstract

Background : Radiation-induced pulmonary toxicity occurs in patients with lung cancer who received irradiation. The objective of this study was to determine the proportion of radiation pneumonitis among lung cancer patients that were exposed to radiation treatment in Persahabatan Hospital. There is no data about proportion of radiation pneumonitis in Indonesia.Methods: This was a retrospective study conducted in Persahabatan Hospital during June 2013– July 2015 using the medical record of lung-cancer patients who received irradiation.Results: 33 lung-cancer patients fulfilled the inclusion criteria. Most of them were male (66.7%), in age ≥ 51 years (63.6%), had a smoking history (75.8%) with moderate Brinkman Index (60%), were given irradiation doses of 3,000–4,000 (60.6%) with irradiation fractions of 10–19 (60.6%), had no history of chemotherapy (54.5%), and were diagnosed with adenocarcinoma (66.7%) and stage-IV cancer (84.84%). The proportion of radiation pneumonitis based on chest X-ray (CXR) was 39.4%; which consisted of hazy ground-glass opacities, hazy ground-glass opacities, and fibrosis, and only fibrosis. There were significant differences in age, radiation doses, and history of chemotherapy with the proportion of radiation pneumonitis (p < .05).Conclusion: The proportion of radiation pneumonitis based on CXR was 39.4%. There were significant differences in age, radiation doses, and history of chemotherapy with the proportion of radiation pneumonitis. 

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Journal Info

Abbrev

ijoc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical ...