Jurnal Farmasi Sains dan Praktis
Vol 8 No 2 (May-August 2022)

STABILITY AND SUNSCREEN ACTIVITY OF NUTMEG SEED OIL EMULGEL WITH CARBOPOL 940 VARIATION AS GEL BASE

Ilma Nur Khafifa (Department of Pharmaceutical, Universitas Wahid Hasyim, Semarang 50232, Indonesia)
Ayu Shabrina (Department of Pharmaceutical, Universitas Wahid Hasyim, Semarang 50232, Indonesia)
M Fatchur Rochman (Department of Pharmaceutical, Universitas Wahid Hasyim, Semarang 50232, Indonesia)



Article Info

Publish Date
30 Jun 2022

Abstract

The nutmeg seed oil has antioxidant and sunscreen activity, but it is unstable in storage. The stability of nutmeg seed oil can be improved by developing the oil into an emulgel with carbopol 940. This study determined the stability of nutmeg seed oil emulgel (NSE) with carbopol 940 as a gel base. NSE contains of 10% nutmeg oil and variation of carbopol 940 were 0.60% (FI), 0.80% (FII), and 1.0% (FIII). NSE was tested for SPF value every week and physical stability, including organoleptic, homogeneity, adhesion, dispersibility, viscosity, and pH before and after 30 days of storage. NSE was stored at the climatic chamber at 30±2°C with RH 65±5%. Quantitative data from physical stability were analyzed by t-test dependent while SPF value and antioxidant were analyzed by univariate test. All the physical parameters showed no significant changes (p > 0.05). Emulgel was white thick, with a nutmeg seed oil odor. pH was in a safe range for skin (6.12-6.90). NSE had pseudo-plastic rheology, and it changed into pseudoplastic-thixotropic after 30 days of storage. The SPF value of NSE was above eight, and it did not show significant change after the storage from each week (p > 0.05). Nutmeg seed oil emulgel with carbopol 940 showed stable physical appearance and SPF value.

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Journal Info

Abbrev

pharmacy

Publisher

Subject

Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science ...