Biomedical Journal of Indonesia
Vol. 6 No. 3 (2020): Vol 6, No 3, 2020

The Effectiveness Of Moringa oleifera L (Moringa oleifera L) Fraction On The Improvement Of Hemoglobine Levels Of Betinine Rat (Rattus norvegicus) Anemia Model Of Iron Deficiency

Winda Ricika (Biomedical Study Program, Faculty of Medicine, Sriwijaya University)



Article Info

Publish Date
03 Nov 2020

Abstract

The iron deficiency anemia is kind of anemia because the less of iron that make the function to tie oxygen is down. Young girl is one of sufferer group who’s prone to get anemia. The long consequence of anemia for the young girl will disturb fatal function of some organ in their body. In general arise of headache symptoms and pain in the centre of head. And the in pregnancy will increase some complication risk such as maternal death. Premature born and perinatal death. One of nature ingredients (herbal) which is reported to have high iron content is kelor leaf (Moringa oleifera L) for about 28, 29 mg/100 g kelor. The purpose of this research is to know the effectivenessof Kelor leave fraction ((Moringa oleifera L) to increase hemoglobin grade with preclinical. Experimental research with complete random design (RAL) has been done in February till April 2019 in medical faculty laboratory of universitas sriwijaya Palembang. Sample of the research is female rat that has inclusion criteria as much 30 rats. Divided into 5 group. That is negative control group. Positive control (ferrous fumarate 60%), n-heksan fraction, ethyl acetate, and 1% concentration of kelor leave ethanol, the data of Hb all of subject before and after treatment from subject of iron deficiency anemia has collected by using Easy Touch GCHb tool. The analysis data of this research used SPSS 2.2 version. The result of the research said that the hemoglobin grade before and after treatment showed significant increasing(p<0,05) for n – hexane fraction and acetate ethyl >45%. While ethanol fraction only 32%.

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Journal Info

Abbrev

bji

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing ...