Optimal Control of HIV-1 Spread in Combination with Nutritional Status and ARV-Treatment

Yolanda Norasia (Walisongo State Islamic University)
Zulaikha Zulaikha (Walisongo State Islamic University)
Mohamad Tafrikan (Walisongo State Islamic University)
Mohammad Ghani (Airlangga University)
Denis Sospeter Mukama (Dar es Salaam University College of Education (DUCE))

International Journal of Computing Science and Applied Mathematics
Vol 8, No 2 (2022)

HIV-1 is a virulent virus, it has the ability to easily spread the virus. This study aims to optimally control the spread of the HIV-1 virus with SIPA (Susceptible-Infection-PreAIDSAIDS) model by using nutritional status and ARV-treatment. Assessment of nutritional status is carried out on people with HIV/AIDS (ODHA). The results showed that the control in the form of nutritional status and ARV-treatment was able to reduce the infected subpopulation. Routine assessment of nutritional status can form balanced nutrition for ODHA. ARV-treatment works by reducing the amount of HIV viral load, so that HIV infection cannot cause disorders of the immune system.