ISM (Intisari Sains Medis) : Jurnal Kedokteran
Vol. 10 No. 1 (2019): (Available online 1 April 2019)

Karakteristik pasien retinoblastoma di RSUP Sanglah pada bulan April 2015 – Desember 2017

Monika Nur Indah Pawana (Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Udayana)
Ni Putu Ekawati (Departemen Patologi Anatomi RSUP Sanglah-Universitas Udayana)
Luh Putu Iin Indrayani Maker (Departemen Patologi Anatomi RSUP Sanglah-Universitas Udayana)



Article Info

Publish Date
01 Apr 2019

Abstract

Background: Retinoblastoma is one of the intraocular tumors originate from the lining of the retinal eye layer component. This disease is more common in children. Retinoblastoma incidence rate tend to be constant every year, but epidemiological data about retinoblastoma in Indonesia not yet available.Aim: this study aims to determine the characteristics of patients with retinoblastoma at RSUP Sanglah Denpasar from April 2015 till December 2017.Method: The study was a descriptive cross sectional design which was conducted at RSUP Sanglah Denpasar. Data obtained was in the form patient’s medical records registered between April 2015 – December 2017.Results: Of the 22 patients, the age average was 5.06 ± 3.06 years with the highest gender proportion was male (55%). Leukokoria (68%) was the main complaint. Most sites were unilateral (59%). Staging for unilateral was Group D (47%) and for bilateral was OD Group D, OS Group E (25%) and OD Grup E OS Grup C (25%) There were two patients had family history of retinoblastoma (18%). Histopathological finding showed only 4.54% with typical appearance of Flexner Wintersteiner Rossete, 36% of patients showed pseudorossete, and the remains classified as undifferentiated type. Almost half of the patients have a tumor invation, and most of them have necrosis in their tumor. The most common management for retinoblastoma is chemotherapy (52%) followed by enucleation (48%). Conclusion: There’re variety in characteristics of retinoblastoma. Further research needed to know the characteristic of retinoblastoma significantly.

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Journal Info

Abbrev

ism

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and ...