ISM (Intisari Sains Medis) : Jurnal Kedokteran
Vol. 10 No. 2 (2019): (Available online: 1 August 2019)

Hubungan kadar troponin I dan high-sensitivity troponin I dengan angiografi koroner pada pasien suspek coronary artery disease: studi di Rumah Sakit Umum Pusat dr.Wahidin Sudirohusodo Makassar-Indonesia tahun 2017

Dessy Iriana (Program Pendidikan Dokter Spesialis Patologi Klinik, Fakultas Kedokteran Universitas Hasanuddin/RSUP dr.Wahidin Sudirohusodo Makassar, Indonesia)
Asvin Nurulita (Program Studi Patologi Klinik, Fakultas Kedokteran, Universitas Hasanuddin/ RSUP dr.Wahidin Sudirohusodo Makassar, Indonesia)
Darmawaty Rauf (Program Studi Patologi Klinik, Fakultas Kedokteran, Universitas Hasanuddin/ RSUP dr.Wahidin Sudirohusodo Makassar, Indonesia)



Article Info

Publish Date
01 Aug 2019

Abstract

Background: Coronary artery disease (CAD) is a narrowing of blood vessels due to the formation of atherosclerotic plaques which can cause disruption of oxygen supply to the heart. High sensitivity troponin I (hs-TnI) is a diagnostic tool for detecting heart disorders with minimal injury to the heart muscle.Aim: The study aimed to compare and observe the relationship of troponin I (TnI) and hsTnI with /RSUP dr.Wahidin  Sudirohusodo Makassar.Methods: The design of the study was cross-sectional study, using primary data of blood samples from 31 suspected CAD patients who underwent coronary angiography examination at RSUP Dr.Wahidin Sudirohusodo Makassar. Samples were taken from a population of subjects who met the inclusion criteria by using consecutive sampling technique in the period of September 2018. Statistical analysis were done using descriptive statistical calculations, frequency distribution and, Spearman’s correlation test. The test results were considered significant if p<0.05.Results: CAD was more common in men at the age of 50-69 years. Data analysis showed a significant correlation between TnI, hsTnI, and the degree of stenosis (p<0.001). The correlation coefficient of TnI and degree of stenosis was 0.707, hsTnI with degree of stenosis was 0.877, and TnI with hsTnI was 0.804.Conclusion: Higher levels of TnI and hsTnI are related to the severity of stenosis in CAD.

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Journal Info

Abbrev

ism

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and ...