Jurnal Indah Sains dan Klinis
Vol. 3 No. 2 (2022)

Formulasi dan Uji Antioksidan Sediaan Krim Ekstrak Etanol Buah Asam Cikala (Etlingera elatior (Jack) R. M. Sm) sebagai Pelembab Kulit

Sudewi (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Nilsya Febria Zebua (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Siti Arum Widiyanti (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Muflihah Fujiko (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Nurul Karimah (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Supran Hidayat (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)
Rahma Yulia (Fakultas Farmasi, Program Studi Sarjana Farmasi, Univeristas Tjut Nyak Dhien Medan, Indonesia)



Article Info

Publish Date
21 Aug 2021

Abstract

Cikala acid fruit is fruit of kecombrang plant (Etlingera elatior) which phenolic compounds including flavonoids and has strong antioxidants activity. Antioxidants are nutrients in the form of vitamins and minerals that function to prevent and repair damaged body tissues. Antioxidant compounds are generally used in cosmetic products. The purpose of this study to determine the antioxidant activity of the ethanolic extract of the cikala fruit was formulated into a moisturizing cream. This research is experimental, covering extract manufacture, phytochemical screening, manufacture and testing of cream preparations as well as testing of antioxidant activity in moisturizing cream. The cream formulation formula was made with a concentration ratio of 1.5%, 2%, 2.5% and blank. Chemical compounds from the ethanolic extract of cikala fruit are alkaloids, saponins, flavonoids and triterpenoids; has a homogeneous cream dosage form with a pH range of 5.7-6.1 after short storage and  12 weeks of storage; and has antioxidant activity with inhibitor concentration value of 19.92 g/mL at concentration 2.5%.

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Journal Info

Abbrev

jisk

Publisher

Subject

Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing

Description

Jurnal Indah Sains dan Klinis adalah Jurnal tentang kesehatan yang mencakup sains dan klinis yang diterbitkan oleh Lembaga Penelitian dan Pengabdian pada Masyarakat (LPPM) STIKes Indah Medan yang meliputi kajian Ilmu Farmasi, Kedokteran, Keperawatan, Kebidanan, Kimia, Biologi, Mikrobiologi, Kultur ...