The role of adequate vitamin D levels in the menstrual cycle of reproductive-age women

Ahila Meliana (Medical Program, Faculty of Medicine, Universitas Airlangga)
Hana Salsabila (Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia)
Bendix Samarta Witarto (Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia)
Manik Retno Wahyunitisari (Department of Medical Microbiology, Universitas Airlangga, Surabaya)

Majalah Obstetri dan Ginekologi
Vol. 30 No. 3 (2022): December

HIGHLIGHTS 1. This study reviews the effect of adequate levels of serum vitamin D on menstrual cycle2. Vitamin D affects the length and regularity of menstrual cycle3. Women with vitamin D insufficiency typically report irregular and prolonged menstrual periods than women with adequate vitamin D levels.   ABSTRACT Objective: This study investigated the role of adequate vitamin D levels in the menstrual cycle of reproductive-age women. Materials and Methods: We systematically searched using certain key words in PubMed and ScienceDirect for English articles, full articles, published between August 2013 - August 2022 that evaluated the effect of vitamin D levels on the menstrual cycle of women in reproductive age. The results were analyzed qualitatively. Results: Eight studies from 653 recorded articles were eligible for review. Decreased vitamin D levels can cause menstrual cycle irregularities, which are related to a decrease in the hormone estradiol, affecting the menstrual cycle. In addition, lower levels of vitamin D lead to longer menstrual cycles. Conclusion: Vitamin D is vital in the menstrual cycle because it influences the frequency and duration of menstruation.