Journal Of Widya Medika Junior
Vol 4, No 4 (2022): October

THE EFFECTIVENESS OF HAEMATOCOCCUS PLUVIALIS EXTRACT ON SUPEROXIDE DISMUATSE LEVEL OF RATTUS NORVEGICUS POST ULTRAVIOLET B EXPOSURE

Angeline G Irwan (Faculty of Medicine, Widya Mandala Surabaya Catholic University)
Endang Isbandiati (Department of Pharmacology, Faculty of Medicine, Widya Mandala Surabaya Catholic University)
Dave G Oenarta (Department of Dermatovenereology, Faculty of Medicine, Widya Mandala Surabaya Catholic University)



Article Info

Publish Date
30 Oct 2022

Abstract

Background : Exposure of ultraviolet B from the sun can trigger the formation of free radicals, and causing oxidative damage on skin. One of the treatments for skin damage caused by UV B exposure is using 2% glutathione cream. and using green algae Haematococcus pluvialis extract cream.Objective : To analize the differences in the effectiveness of giving Haematococcus pluvialis extract cream and glutathione cream on white rats post ultraviolet B exposure.Method : The type of research used in this study is experimental with the post test only control group design approach. The number of samples was calculated using the Federer formula, with a total sample of 30 white rats that are devided into 6 groups. The parameter is superoxide dismutase enzim that is measured using spectrophotometer.Result : As a normal control group, 5 white rats were not exposed to UV B and were not given any cream while 25 white rats were exposed to UV B light for 2 hours in 14 days, then 5 rats as negative control group were not given any cream, 5 rats as positive control group were given 2% glutathione cream, 5 rats were given 10% Haematococcus pluvialis cream, 5 rats were given 20% Haematococcus pluvialis cream, and 5 rats were given 30% Haematococcus pluvialis cream. The results of this research showed that rats that were given 20% and 30% Haematococcus pluvialis cream has higher superoxide dismutase levels than the other groups.Conclusion : Haematococcus pluvialis extract cream is effective in treating oxidating damage on white rats post ultraviolet B exposure.

Copyrights © 2022






Journal Info

Abbrev

JWMJ

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Journal of Widya Medika Junioris our faculty's very first project in publishing the students' research, making them available for both students and faculty members to read. It is an endeavour to nurture our students' passion in doing scientific research through which process they will be encouraged ...