<![CDATA[Objective: This study aims to determine whether the extract of pineapple cobs has an antibacterial effect on the growth of Streptococcus mutans. In addition, it is to find out the minimum inhibitory concentration of pineapple cobs extract on the growth of Streptococcus mutans. Material and Methods: This research is an experimental laboratory research in vitro. Pineapple cobs extract was diluted with DMSO which was used as a negative control.Antibacterial effectiveness test was carried out using the diffusion method to use disc paper. Calculation of minimum inhibitory content (MIC) is done by measuring the clear zone around the disc paper using calipers. Results: Pineapple hump extract with a concentration of 50%, 25% and 12.5% have an average diameter of 7.50mm, 6,175mm and 6.15mm. Pineapple cobs extract with a concentration of 3.125% did not show any clear zone. Therefore the minimum inhibitory concentration (MIC) of pineapple cobs extract on the growth of Streptococcus mutans is 6.25%. Conclusion: Research shows the antibacterial effect of pineapple cobs extract in inhibiting the growth of Streptococcus mutans bacteria. Minimum inhibitory concentration(MIC) is a concentration of 6.25%.]]>
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