MEDICINUS
Vol. 35 No. 3 (2022): MEDICINUS

Sistem Penghantaran Obat dengan Misel Polimer

Alasen Sembiring Milala (Unknown)



Article Info

Publish Date
01 Dec 2022

Abstract

Today is the era of nanotechnology, where almost all fields use nanotechnology. Likewise, the field of pharmaceutical technology is currently intensively developing pharmaceutical preparations using nanosystem. One of these nanosystems is polymeric micelles, which generally have particle size below 100 nm. Research showed that polymeric micelles have been proven to increase the solubility and bioavailability of hydrophobic drugs. There are several methods that can be used in polymeric micelles preparation, each of which has advantages and disadvantages. In order to characterize polymer micelles, parameter evaluation includes determination of critical micelle concentration (CMC), particle size, surface characteristics, stability, and release tests. Although most of the research on polymer micelles was applied in the field of oncology by the intravenous route of administration, researchers are currently developing drug delivery system using polymer micelles for oral route of administration. It can be further expected to initiate clinical research like such that has been done on intravenous administration.

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Journal Info

Abbrev

journal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Tujuan penerbitan jurnal Medicinus adalah untuk meningkatkan wawasan dan menambah khasanah pengetahuan para praktisi medis dan farmasis di bidang kedokteran dan kefarmasian. Ruang lingkup dari jurnal ilmiah ini adalah publikasi artikel-artikel ilmiah yang bisa disajikan dalam bentuk penelitian ...