Journal of Science and Applicative Technology
Vol 6 No 2 (2022): Journal of Science and Applicative Technology December Chapter

UJI AKTIVITAS EKSTRAK BUNGA KECOMBRANG (Etlingera elatior Jack) SEBAGAI HIPOLIPIDEMIA PADA TIKUS WISTAR OBESITAS

Sri Wardani (Program Studi Kimia, Fakultas Matematika dan ilmu Pengetahuan Alam, Universitas Udayana, Bali, Indonesia)
Ni Wayan Bogoriani (Program Studi Kimia, Fakultas Matematika dan ilmu Pengetahuan Alam, Universitas Udayana, Bali, Indonesia)
Ni Luh Rustini (Program Studi Kimia, Fakultas Matematika dan ilmu Pengetahuan Alam, Universitas Udayana, Bali, Indonesia)



Article Info

Publish Date
29 Dec 2022

Abstract

Kecombrang (Etlingera elatior Jack) is a plant that has potential for hypolipidemia. Kecombrang has secondary metabolites consisting of tannins, saponins, alkaloids, steroids, terpenoids, phenolics, and flavonoids. The purpose of this study was to determine the hypolipidemic activity of kecombrang flower methanol extract in obesed Wistar rats fed a high-fat diet. The test animals used in this study were 18 female white rats aged two months, weight of ± 150 grams. The test animals were divided into three groups, namely normal control (only given standard feed), high-fat control (obesed rats with high-fat diet), and flower treatment group (obesed rats with a high-fat diet + flower methanol extract 100 mg/kgBW) orally for 30 days. The results showed that kecombrang flowers reduced total cholesterol levels by 55.5%, triglycerides (TG) by 57.4%, LDL by 76.73%, and increased HDL by 42.96%. The kecombrang flower has the potential for hypolipidemia which is characterized by a decrease in total cholesterol, TG, LDL, and can increase HDL levels in obese rats significantly (p<0.05).

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Journal Info

Abbrev

jsat

Publisher

Subject

Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Engineering Materials Science & Nanotechnology Mechanical Engineering

Description

Journal of Science and Applicative Technology is soon indexed by google scholar, SINTA (Science and Technology Index), portal garuda, DOAJ (Directory of Open Access Journals). This journal has been registered at PDII LIPI (ISSN: 2581-0545). This journal is semiannual journal. It will be published in ...