Heart Science Journal
Vol 4, No 1 (2023): Optimizing Outcome in Acute Cardiac Care

Risk Factors for Acute Kidney Injury in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention

Yudi Putra (Brawijaya Cardiovascular Research Center)
Budi Satrijo (Brawijaya Cardiovascular Research Center)
Setyasih Anjarwani (Brawijaya Cardiovascular Research Center)
Indra Prasetya (Brawijaya Cardiovascular Research Center)
Anna Fuji Rahimah (Brawijaya Cardiovascular Research Center)



Article Info

Publish Date
29 Jan 2023

Abstract

BackgroundAcute kidney injury (AKI) is a frequent complication of ST-Elevation Myocardial Infarction (STEMI). AKI occurs in about 10% to 20% of patients with STEMI, which significantly impacts both short-term and long-term clinical outcomes.ObjectivesWe purposed to identify the risk factors for AKI among STEMI patients undergoing Primary PCI.MethodsThis retrospective cohort study analyzed 568 STEMI patients who underwent Primary PCI from 2017 to July 2022 at Saiful Anwar General Hospital Malang. We conducted both univariate and multivariate studies to determine AKI risk factors.ResultsThe risk factors for AKI among STEMI patients undergoing primary PCI were identified. The OR values for each were as follows: Shock condition (OR = 1.41; 95% CI = 1.18 – 1.92); Killip ≥3 (OR = 3.54; 95% CI = 2.14 – 4.26); and total contrast volume> 145 ml (OR = 1.61; 95% CI = 1.13 – 1.92). Based on the ROC curve analysis, total contrast volume >145 ml with an area under the curve (AUC) of 0.75 (95% CI = 0.65-0.85) with a specificity of 0.66 (95% CI = 0.61 – 0.71) and a sensitivity of 0.71 (95% CI = 0.65-0.76).ConclusionOur study revealed that the risk factors for AKI among STEMI patients undergoing primary PCI were shock condition, Killip class ≥3, and total contrast volume >145 ml.

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Journal Info

Abbrev

heartscience

Publisher

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology

Description

HEART SCIENCE is the official open access journal of Brawijaya Cardiovascular Research Center, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. The journal publishes articles three times per year in January, May, and September. The ...