<![CDATA[The present study was aimed to investigate MetheletetraHydrofolatredctase (MTHFR) gene which related to acute myocardial infarction (MY) patients using restriction fragment length polymorphism (RFLP-PCR) technique, the results show that the homozygote TT genotype was (23.3%) in patients and (30.0%) in control with non-significant variation (OR 1.41). while CT genotype was (30.0%) and (33.03%) in patent and control respectively with not significantly with OR (14.414) , CC genotype was (46.7%) in patients and (36.70%) in control. The allelic frequency was T patient vs. controls; 38% vs. 47% while allelic frequency was C in the patient vs. controls; 62% vs. 53%. we have concluded that the MTHFR 677T allele hasn’t been contributed as a risk factor for myocardial infarction .Our findings raise the possibility that novel genetic defects and/or environmental factors may influence homocysteine metabolism in this ethnic group.Keywords: MetheletetraHydrofolatredctase, Acute myocardial infarction, RFLP-PCR.]]>
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