Journal of Global Pharma Technology
Volume 09 Issue 12

Synthesis of a New Three-Dimensional Network Co-polymer and Studying the Ability of Drug Delivery System

Zahraa Mushtaq Abd Al-Aama (Unknown)



Article Info

Publish Date
13 Jan 2018

Abstract

In this work, a new co- polymer was synthesized from the reaction of pentarythritol with fumaric acid to form the linear co- polymer. Three different moles of acrylic acid monomer (0.5, 1.0 and 1.5 mole), were added to obtain three new co- polymers. Swelling of the polymer samples were measured in the buffer solution in the basic and acidic medium. The albumin protein was loaded onto the co- polymer samples and then the release of the albumin protein was measured in the acid and basic medium. The results obtained showed that the protein loading and release process in the basic medium were higher than in the acidic medium, indicating that the combined co-polymer is selective in the medium.Keywords: Hydro gel; Polymer; Condensation polymerization; Three-dimensional network; Selectivity; Swelling; Buffer solution;  Drag delivery system.

Copyrights © 2018






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...