<![CDATA[The study includes the preparation of 12 new derivatives of heterogeneous cyclic derivatives of bendazole. The hydrazid (A1) derivatives of bendazole reaction with hydrazine in absolute ethanol were prepared, and from its reactor (A1) with 4-diethylamine benzaldehyde (A2). The ring closure was performed using succinic anhydride to obtain the oxazepine ring (A3). Carboxylic acid derivative (A4) was prepared from hydrolysis of bendazole using concentrated hydrochloric acid, and its derived reactor (A4) with thainoid chloride obtained the acid chloride derivative (A5). After that the derivative (A6) was synthesized from its A5 derivative reacted amino acid glycine in NaOH (10%). ring closure was then performed using a number of different aromatic aldehyde with acetic anhydride to obtain the oxazole ring (A7a, A7b). (A7a, A7b) were obtained and obtained derivatives (A8a, A8b), which were used in two different routes. First track obtained the pyrazole (A9a, A9b) by ring closure the reacted with hydrazine. The other path was to obtain hydrazide derivatives (A10a , A10b) by interacting with the aromatic aldehyde to obtain Schiff bases (A11a, A11b) and then conduct the ring closure of the derivatives above for derivatives (A12a, A12b). The compounds prepared by melting points, infrared spectra and H1NMR were diagnosed. Biochemical efficacy was also assessed.]]>
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