Journal of Global Pharma Technology
Volume 11 Issue 03

The Effect of Calcium Oxide Nanoparticles on Liver Enzymes in White Rats

Shurooq Wesam Al-Shaibani (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

Calcium is the five elements that found on the crust of the earth. It`s the essential mineral for all organisms because the important role in the functions of the life cells , and its essential mineral for binding the bone and teeth by producing calcium phosphate. The decreasing of calcium element in the body leads to weakness, dental caries, and muscle cramps. Present study was designed to evaluate the effect of calcium oxide- nanoparticles on the serum levels for liver enzymes of white rats. Two group of White rats ( 3 rats each group) received calcium oxide- nanoparticles which were orally administered with 50 and 100 (mg/kg) from of body weight of calcium oxide- nanoparticles suspension daily for 10 day. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) were measured at start and at the end of the study.  Changes of the specific parameters indicated that liver were significantly affected in both experimental groups , the changes between the levels of total alanine aminotransferase , aspartate aminotransferase and alkaline phosphatase indicate that calcium oxide- nanoparticles induces liver damage and may be lead to hepatic toxicity in the experimental rats.Key words: CaO-Nanoparticles, (ALT, AST and ALP), White rats.

Copyrights © 2016






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...