Journal of Global Pharma Technology
Volume 12 Issue 02 (2020) Feb. 2020

Evaluate Toxic Effect of Bisphenol A on Kidney of Male Mice and Mitigation Its Effect by Green Tea Extract

Aamer. M. Ali (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

Bisphenol A is a substance for the synthesis variety of plastics, primarily epoxy resins and polycarbonates. Bisphenol can have severe effects on the type and might contribute to gradual cumulative renal injury over a lifetime. This study object to estimate toxic effect of bisphenol A on type of male mice also mitigation toxic effect of bisphenol A by using extract green tea. Healthy adult male albino laboratory mice (Mus musculus) treated for two doses of bisphenol a (20 mg/kg and 40 mg/kg body weight per day) for thirty days and green tea extract was co-administration orally as antioxidant. Bio-chemical parameter of serum creatinine and blood urea was calculated as indicator of kidney function. groups treated with bisphenol A showed increased in serum creatinine and blood urea also histopathological of kidney showed significant damage in groups that treated with bisphenol A whereas groups that treated with bisphenol A and co-administration  green tea extract showed mitigation toxic effect of bisphenol  A due to role of green tea as anti-oxidant compound.Keywords:  Evaluate, Bisphenol A, Green Tea, Antioxidant compound.

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Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...