Synthesis, Characterization, Antimicrobial Activity and Antioxidant of Azo Schiff Bases Containing Sulfanilamide

Bushra K. AL-Salami

Journal of Global Pharma Technology
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Some new azo Schiff bases (SH1-SH6, SH14) were prepared in good yields by reaction of Sulfanilamide with 2, 4-dihydroxy-5-(phenyldiazyl) benzaldehyde and its substituted derivatives (Z1-Z6, Z14).  The structures of azo and azo-azomethine compounds were determined by FT-IR, 1HNMR spectroscopic techniques, EI-mass and elemental analysis.  The azo-azomethine compounds have been tested in vitro against Pseudomonas aeruginosa (-Ve) gram and Staphylococcus sciuri (+ Ve) gram in order to assess their antibacterial characteristic. Antioxidant efficiency of the azo-azomethine compounds examined.Keywords: Azo-azomethine, Azo compound, antioxidantand antibacterial activity, Sulfanilamide.