Journal of Global Pharma Technology
Volume 11 Issue 2: 2019

New Mixed Ligand Complexes; Synthesis, Spectral Analysis and Biological Activity

Enaam Ismail Yousif (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

The formation, structural characterization of mixed ligand complexes of Co II, Zn II, Cd II and Hg II metal ions with the Schiff base ligand (Z)-3,4,5-trihydroxy-N'-(4-hydroxybenzylidene) benzohydrazide and 8-hydroxyquinolineare reported. Ligand and complexes were characterized by analytical and spectroscopic analyses including; FTIR, electronic and 1H, 13C-NMR spectroscopy, microanalysis, chloride content, thermal analysis, magnetic susceptibility and conductance. Physico-chemical techniques indicated the formation of complexes with four-coordinated arrangement in the solid and solution state. Biological activity of the prepared ligand and their mixed complexes were screened for their antimicrobial activity against four bacterial species (Staphylococcus aureus and Bacillus subtitles (G+)), Enterobacter and Escherichia coli (G-)). Biological data showed that complexes become potentially more active against these tested bacteria compared with the free ligandsKeywords: Mixed ligand complexes, Structural characterization, Spectral analysis, Biological activity.

Copyrights © 2019






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...