Journal of Global Pharma Technology
Volume 11 Issue 07

Serum Monoamine Oxidase (A and B) Activities and Oxidative Stress Status in Iraqi Infertile Women Undergoing In Vitro Fertilization

Shatha Abdul Wadood Al- Shammaree (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

Serum monoamine oxidase (MAO-A and B) activities were measured in 98 infertile women undergoing in vitro fertilization (Intracytoplasmic Sperm Injection ICSI) attending Kamal AL-Samaree Hospital for Infertility and In Vitro Fertilization at Baghdad after treatment with standard long protocol. Methods: Participants in the study were 98 infertile women subdivide according to infertility cause into PCOS, Unknown cause, and Male factor cause. The activities of MAOs, some antioxidant, and oxidant parameters (catalase, thiol levels, and lipid peroxidation product (MDA) were measured. Luteinizing hormone (LH), Follicle stimulating hormone (FSH), LH/FSH ratio, TSH and prolactin were measured. Results: The activities show significant variations among the three infertility groups. Serum MAOs activities (MAO-A, MAO-B) in sera of PCOS (P<0.01), as well, MDA, and total thiol levels were higher significantly when compared with other groups .While, the activity of catalase was lower significantly (p<0.001). Conclusion: Our study reveals the existence of an imbalance between serum oxidant and antioxidant status in infertile women with PCOS undergoing IVF.Keywords: Monoamine Oxidase Activity, Ovary Polycystic Syndrome, Unknown Infertility, Oxidative Stress.

Copyrights © 2016






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...