DAGUSIBU is an acronym of to get, to use, to keep and to throw the medicine away appropriately in Indonesia. The Indonesia Pharmacist Association already launched this acronym to support the appropriate use of medicine. However, some efforts are needed to be conducted to understand about the dissemination of DAGUSIBU in community. This study is aimed to define the effectiveness of the health promotion in the increase of knowledge of the community cadres in one of community district in Yogyakarta, IndonesiaThis study used quasi experimental, one group pre-posttest design. The respondents were all community cadres in Muja Muju, Yogyakarta Indonesia. The health promotion with DAGUSIBU topic by the pharmacist was conducted as the health promotion media. The questionnaire was given to the respondents before and after the health promotion.We recruited 39 community cadres from Muja Muju Yogyakarta. Most of the respondents are female (94.9%), with the average of age is 54.5 years old. The community cadres’ knowledge increased significantly from 38.4 to 80.1 (p<0.001). Respondents’ characteristics, such as age, sex and education did not predict the increase of community cadres’ knowledge about DAGUSIBUThe health promotion of DAGUSIBU conducted by pharmacist can improve the community cadres’ knowledge. This model can be used to disseminate DAGUSIBU effectively in community level.
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