Journal of Global Pharma Technology
Volume 11 Issue 07

Animal Model of Pancytopenia and Bone Marrow Function Diagnosis of Domestic Rabbits

Mohammed E. Mansur (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

The present research aims at showing the effects of extracts of some plants seeds (Nigella sativa, Medicago sativa, Eruca sativa, Ocimum basilicum, Vitis vinifera, Portulaca oleracea) in animals that are induced by a type of drug Azathioprine as animal model of pancytopenia. Several reports have shown that plant extracts are used as an alternative to chemotherapy in many cases of diseases. The research was conducted on forty white rabbit (five weeks old), after weaning, weighing between 500-700 grams, the method of work included eight groups, the numbers of blood cell types that indicate the effectiveness of bone marrow were measured ( RBC, WBC, Thrombocytes, IRF, IPF,IGs, Schistocytes, reticulocyte and ANC),the extracts showed different effects in terms of their ability to improve or re-develop bone marrow to produce blood cells, Ocimum basilicum extract showed a higher effect than the rest of the extracts in pancytopenia treatment, which gave a clear effect on improving bone marrow efficiency.

Copyrights © 2016






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...