Journal of Global Pharma Technology
Volume 12 Issue 11 (2020) Nov. 2020

Sperm Quality in HIV-1 Seropositive Men under Antiretroviral Therapy at HIV Integrated Clinic of Dr. Ciptomangunkusumo Hospital, Jakarta, Indonesia

Margaretha Napitupulu (Unknown)



Article Info

Publish Date
29 Oct 2020

Abstract

The effect of human immunodeficiency virus (HIV) infection on male fertility as assessed by sperm quality is still in controversy in various studies. On the other hand, HIV seropositive men who are stable under the influence of antiretroviral therapy (ARV) experienced an increase in quality and life expectancy that allow them to have offspring. This study aims to investigate the sperm quality of HIV seropositive men in Indonesia. In addition, this study also compared sperm quality in HIV seropositive men who were stable under the influence of ARV (case group) with HIV seronegative men (control group). Semen samples from HIV seropositive male patients at the HIV Integrated Clinic, Ciptomangunkusumo Hospital, Jakarta, Indonesia were collected and analyzed for sperm in the laboratory, including: volume, pH, concentration, motility, morphology and sperm vitality. Comparison of sperm quality between the two groups was analyzed using independent t-test and Kruskal-Wallis test. Significant decrease in sperm quality was shown in the concentration, percentage of progressive motility and sperm vitality (p

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Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...