Journal of Global Pharma Technology
Volume 10 Issue 11 (2018) November 2018

Computational Analysis of MK2 Protein for HT Carcinoma Cells using Pre-Processing and Characterization Techniques for Cell Death/ Survival

Shruti Jain (Jaypee University of Information Technology)



Article Info

Publish Date
01 Nov 2018

Abstract

This paper presents the computational analysis using pre-processing and different characterization of MK2 proteins for cell death/ survival for HT carcinoma cells. Initially data is collected which than pre processed by completing the missing data, removing various outliers, checking whether the data is normal or non- normal. Later various characterisation steps were applied which includes: classification, regression, clustering, association rules etc. Different data variables use different approaches of pre processing and characterisation. In this paper we have collected the different data of MK2 proteins where we have cleaned the data by using various clustering approaches, than regression analysis, correlation matrix and covariance matrixes are calculated. In last we have classified the data by using different machine learning approaches (k-NN, SVM and Neural network). For k-NN we have compared the results of different techniques like chebyshev, city block and Euclidean. For SVM we have used linear, polynomial, RBF and sigmoid function for both types (Type 1 and Type 2) and for neural network we have calculated training, test and validation perfection using different hidden, and output activation function. This paper shows best 10 network using MLP and RBF approach. 

Copyrights © 2018






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...