Journal of Global Pharma Technology
Volume 11 Issue 05.

Synthesis and Characterization of Some New Di-amines Derived from Di-amines Supplemented with Di-heterocyclic Five Membered Rings and Some Aromatic Aldehydes

Noor S. Noori (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

It has been documented that imines and heterocyclic compounds with five membered rings and their derivatives, have enormous biological activity in various area as medicinal and pharmaceutical. Therefore, supplementing the di imines with five -membered heterocyclic rings, perhaps enhance the biological activity characters of the resulting products. Consequently, the target of present work involve the developing of new imines derived from selected di amines after connecting a five membered heterocyclic rings of the type di thiazole and di oxazole to the parent molecules via the reaction of the previous di amines with chloroacetyl chloride yield the corresponding amides [A1-A3] , then subsequent reaction of the laterĀ  with of thiourea and urea give substantially new di thiazol [th1-th3] and di oxazole [Ox1-Ox3] respectively .Reaction of these new developed di amines with selected aromatic aldehydes result a pavantly in the formation of the desired bis imines [Sc1-Sc10]. On the other hand the structures of all the synthesized compounds were confirmed by their physical properties, such as colors and melting points and spectroscopic measurements FT-IR, 1H-NMR and 13C-NMR for selected compounds.Keywords: Di imines, Chloroacetyl chloride, Thiazole-2, 4-diamines, oxazole-2, 4-diamines.

Copyrights © 2016






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...