Deteksi Varian Rhesus Dweak pada Populasi Rhesus Negatif di Provinsi DKI Jakarta

Endang Pratiwi (Program Magister Ilmu Biomedik, Fakultas Kedokteran, Universitas Indonesia)
Ni Ken Ritchie (UDD PMI Provinsi DKI Jakarta)
Heri Wibowo (Departemen Parasitologi, Fakultas Kedokteran, Universitas Indonesia)

Media Ilmu Kesehatan
Vol 11 No 2 (2022): Media Ilmu Kesehatan

Background: The Rhesus blood group system is determined by the presence or absence of the D-antigen, and has clinical importance because it can cause Haemolytic Transfusion Reaction (HTR) and Haemolytic Disease of the Newborn (HDN). There are several variants of the D-antigen which are weak, so it will be detected as Rhesus Negative.Objective: The purpose of this study was to determine the prevalence of the Rhesus D weak blood group variant in DKI Jakarta Province, so that it could determine the identity status of the blood group correctly.Methods: The samples used in this study were whole blood samples with a maximum storage time of three days in the blood refrigerator. The examination used in this study is the Indirect Antiglobulin Test (IAT).Results: Rhesus Dweak variant was detected in 103 samples examined using the IAT examination method.Conclusion: Determination of the Rhesus variant in individuals is necessary to prevent clinical impact on the patient. Further examination is needed to ensure the D-antigen of the Rhesus blood group