Journal of Maternal and Child Health
Vol. 6 No. 6 (2021)

Neutrophil-Lymphocyte Ratio as a Diagnosis Predictor in Pediatric COVID-19 Patients at Dr. OEN Kandang Sapi Hospital, Surakarta, Central Java, Indonesia

Retno Edi, Dyah Wulaningsih (Unknown)
Nugroho, Irfan Dzakir (Unknown)



Article Info

Publish Date
16 Nov 2021

Abstract

Background: COVID-19 is a global pandemic and affects all ages, even newborns. Until March 2021, there were 127 million cases of COVID-19 worldwide. In Indonesia, there were almost 1.5 million cases. The main symptoms of COVID-19 are fever and cough, simple laboratory tests such as measuring the neutrophil-lymphocyte ratio (NLR) are also included in the EWS (early warning score) so that they can be used to diagnose COVID-19 with a cut-off limit value of 3.13. The purpose of this study was to determine the value of NLR as a predictor of diagnosis in pediatric patients confirmed by RT-PCR Swab examination at Dr. Oen Kandang Sapi Hospital, Solo, Surakarta. Subjects and Method: A diagnostic test study that assessed the sensitivity, specificity, negative predictive value and positive predictive value of the NLR value as a predictor of COVID-19 diagnosis in pediatric patients confirmed by RT-PCR Swab examination at the time level of March 2020 - March 2021. Data were taken from electronic medical records of inpatients and sampling was done by consecutive admission sampling. Results: A total of 153 study subjects with 34 PCR (+) patients and 119 PCR (-) patients. The characteristics of the study sample were seen from gender, age, symptoms, chest x-ray and patient outcomes. The NLR cutoff limit value for pediatric COVID-19 patients is 1,625 with an AUC (area under curve) of 0.504. The NLR value of 1.625 has a sensitivity of 0.588 (58.8%) and a specificity of 0.513 (51.3%). The PPV (positive predictive value) was 0.256 (25.6%), the NPV (negative predictive value) was 0.813 (81.3%), the PPR (positive predictive ratio) was 1.207 and the NPR (negative predictive ratio) result was 0.803. Conclusion: The NLR cutoff value of 1,625 with a sensitivity of 58.8% cannot be used as a predictor of COVID-19 diagnosis in pediatric patients at Dr. Oen Kandang Sapi Hospital, Solo, Surakarta.

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Journal Info

Abbrev

thejmch

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Journal of Maternal and Child Health (JMCH) is an electronic, open-access, double-blind and peer-reviewed international journal, focusing on maternal and child health. The journal began its publication on July 11, 2015, and is published four times yearly. JMCH aims to improve the policy, program, ...