JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
JKKI, Vol 14, No 1, (2023)

The potential of sweet orange (Citrus sinensis) in cardiovascular health: A literature review

Gabriella Stephanie Minami (Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)
Ellya Catharine Lumbantoruan (Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)
Puteri (Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)
Risa Nuraini (Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)
Joan Carmen Harianto (Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)
Andhi Fahrurroji (Department of Pharmaceutics and Technology of Pharmacy, Faculty of Medicine, Universitas Tanjungpura, Pontianak, Indonesia)



Article Info

Publish Date
05 Apr 2023

Abstract

Consumption of fast food and sedentary lifestyles has recently developed in society. This activity is one of the causes of various degenerative diseases, including cardiovascular disease. Therefore, efforts are needed to prevent it. Sweet orange (Citrus sinensis) is one of the most common types of citrus fruit, with total production reaching 70% of all types. This type of fruit is the most widely produced and consumed by the world’s population. Sweet orange is known for its bioactive compounds that have many benefits in cardiovascular health, such as alkaloids, flavonoids, tannins, phenols, vitamins C, B1, B2, and B3, glycosides, coumarin glycosides, folic acid, some organic acids, essential oils, and saponins. Flavonoids are components of secondary metabolites that play a role in the cardiovascular system. The main components of these compounds are hesperidin and naringenin. Various studies have shown that these compounds are active in reducing hyperlipidemia, improving endothelial function, acting as an anti-inflammatory and anti-atherosclerotic agent, preventing myocardial infarction, and preventing cardiac hypertrophy through various mechanisms with low toxicity.

Copyrights © 2023






Journal Info

Abbrev

JKKI

Publisher

Subject

Medicine & Pharmacology Public Health

Description

JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and ...