Journal of Science and Technology Research for Pharmacy
Vol 2 No 1 (2022)

The The Effect Of Uncontrolled Addition Of Gelatin In Paracetamol Tablet Formulation And The Evaluation




Article Info

Publish Date
05 May 2023

Abstract

Acetaminophen is a pain-relieving (analgesic) and fever-treating (antipyretic) medication that can be obtained over-the-counter. Wet granulation evaluation of granule among others flow time, angle of repose, tapped density tableting evaluation tablet among others weight uniformity, friability, disintegration time tablet flow time evaluation test was 0.16 with an angle of repose 51.78 tapped density of 30%. Tablet manufacturing process, tablet was damaged during the initial printing, namely capping. The tablet evaluation test obtained weight uniformity 248mg, friability 3.22%, disintegration time 1 minute, dissolution results at 60th minutes is 2.2817. The formulation of paracetamol tablets made by the researchers did not meet the specifications for marketability, where the discrepancy in tablet specifications occurred in the physical and chemical properties of the tablets.

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Journal Info

Abbrev

JSTRP

Publisher

Subject

Chemistry

Description

Journal of Science and Technology Research for Pharmacy is open access, peer-reviewed journal published by Pharmaceutical Science Study Program, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Indonesia. The journal publishes only papers describing original findings and ...